Least squares regression models are often used to analyze unbalanced fixed effect data sets with u unique cells defined by design or by post-hoc stratification. Constraints exist among the regression coefficients if there are more coefficients than cells. Models with fewer linearly independent regression coefficients than cells or with empty cells impose constraints on estimated cell means. An easy method of determining constraints among the estimated cell means and among the estimated regression coefficients for any model is developed and illustrated using a small data set. © 1991 by Marcel Dekker, Inc